This is the second post in a series of posts about the hows and whys of cardiac simulation, both electrophysiological and mechanical. The first and previous post was Conceptual Background.
In this post, I’ll catalog the ionic models and plug-ins currently available for use in the CARP simulator.
- MBRDR Modified Beeler-Reuter-Drouhard-Roberge
- PASSIVE R/C circuit model
- COURTEMANCHE Courtemanche human atrial
- LRDII Luo-Rudy Dynamic guinea pig ventricular
- LRDII_F LRD_II with IK(Na)
- NYGREN Nygren human atrial model
- TT ten Tusscher human ventricular
- PUG Puglisi-Bers LRD_II with heart failure modifications
- RNC Ramirez-Nattel-Courtemanche canine atrial
- DiFranNoble DiFrancesco-Noble sino-atrial node
- TT2 ten Tusscher 2 human ventricular with improved restitution and calcium handling properties
- TTRED Simplified (REDuced) version of TT2
- Kurata Kurata improved sino-atrial node
- UCLA_RAB Shiferaw-Mahajan rabbit ventricular
- FHN_RMcC FitzHugh-Nagumo phenomenological model with undershoot removed
- MacCannell_Fb MacCannell fibroblast
- AlievPanfilov Aliev-Panfilov modification of FitzHugh-Nagumo phenomenological model to better match canine action potentials
- SC Shrier-Clay embryonic chick atrial
- LMCG Lindblad-Murphey-Clark-Giles rabbit atrial
- LR1 Luo-Rudy guinea pig ventricular
- EP Krassowska non-resealing electroporation
- Muscon Hunter-McCulloch-ter Keurs fading memory muscular contraction model
- SAC_KS Kohl-Sachs Stretch Activated Channel, model parameters actually obtained from Tavi-Han-Weckstrom
- IF_KZP Zorn-Pauly human atrial If current
- EP_RS Debruin resealing electroporation
- IA shock-activated current Ia
- IFun hyperpolarization-activated “funny” inward current required for anode break excitation
- I_KATP Ferrero K(ATP) current
- I_ACh [ACh]-dependent K channel
- ExcConNHS Excitation-contraction coupling
Available plugins:
Is there a model you’d like to use with CARP that’s not on this list? Please let us know!
